Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Medication for pain relief, constipation, heartburn__6154-both_sexes-4 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL22980, NEUREXINS AND NEUROLIGINS, AND REGULATION OF PRESYNAPSE ASSEMBLY |
| Enrichment Score (ES) | 0.56629103 |
| Normalized Enrichment Score (NES) | 1.1937327 |
| Nominal p-value | 0.113 |
| FDR q-value | 0.413204 |
| FWER p-Value | 0.99 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | DLGAP4 | 107 | 2.513 | 0.1766 | Yes |
| 2 | LRRTM1 | 218 | 2.126 | 0.3248 | Yes |
| 3 | DLGAP3 | 1026 | 1.332 | 0.3769 | Yes |
| 4 | GRM1 | 1819 | 0.986 | 0.4046 | Yes |
| 5 | NLGN1 | 1872 | 0.968 | 0.4720 | Yes |
| 6 | CBLN2 | 1898 | 0.959 | 0.5402 | Yes |
| 7 | FBXO40 | 3632 | 0.603 | 0.4880 | Yes |
| 8 | HOMER2 | 3681 | 0.596 | 0.5286 | Yes |
| 9 | SLITRK5 | 3764 | 0.582 | 0.5663 | Yes |
| 10 | NLGN2 | 4442 | 0.500 | 0.5651 | No |
| 11 | CNTN4 | 5397 | 0.415 | 0.5423 | No |
| 12 | CLSTN3 | 7404 | 0.285 | 0.4518 | No |
| 13 | DLG2 | 7953 | 0.256 | 0.4401 | No |
| 14 | HOMER3 | 8018 | 0.252 | 0.4549 | No |
| 15 | CDH9 | 8842 | 0.219 | 0.4252 | No |
| 16 | SYNGAP1 | 11509 | 0.133 | 0.2871 | No |
| 17 | NRXN2 | 11821 | 0.126 | 0.2790 | No |
| 18 | SHANK1 | 11975 | 0.122 | 0.2794 | No |
| 19 | DLG4 | 12035 | 0.121 | 0.2850 | No |
| 20 | GRM5 | 12193 | 0.117 | 0.2848 | No |
| 21 | TJAP1 | 13206 | 0.095 | 0.2356 | No |
| 22 | NRXN3 | 13950 | 0.081 | 0.2003 | No |
| 23 | SHANK3 | 14260 | 0.075 | 0.1886 | No |
| 24 | HOMER1 | 14795 | 0.066 | 0.1639 | No |
| 25 | SHANK2 | 15340 | 0.058 | 0.1379 | No |
| 26 | NRXN1 | 15792 | 0.050 | 0.1165 | No |
| 27 | LHFPL4 | 15866 | 0.049 | 0.1160 | No |
| 28 | DLGAP1 | 15984 | 0.046 | 0.1129 | No |
| 29 | NLGN4X | 16243 | 0.041 | 0.1016 | No |
| 30 | CBLN4 | 16519 | -0.000 | 0.0864 | No |
| 31 | DLG3 | 16599 | -0.000 | 0.0820 | No |
| 32 | CBLN1 | 16703 | -0.000 | 0.0763 | No |
| 33 | MDGA1 | 16810 | -0.000 | 0.0704 | No |
| 34 | GRID2 | 17261 | -0.000 | 0.0455 | No |
| 35 | PTCHD1 | 17427 | -0.000 | 0.0363 | No |
| 36 | NLGN3 | 17813 | -0.000 | 0.0150 | No |
